In Vitro Study of Antimicrobial Activity of Salacia chinensis Against Methicilin Resistance Staphylococcus aureus (MRSA)

Authors

S. Manju, Bharathiar University, Tamilnadu, India.

K. Moorthy (Associate Professor), Vivekanandha College of arts and Sciences for women, Tiruchengode, Tamilnadu, India.

Abstract

Due to the rapid development of microbial resistance to antibacterial agents, it has become crucial to screen effective, safe, cheap and available therapeutic agents from various medicinal plants to find potential antibacterial effects. In the present study, MRSA isolates were procured from clinical laboratory and inhibited with solvent extracts of Salacia chinensis. Among the two solvents, methanol showed highest phytochemical compounds than chloroform extract. Alkaloids Sterols, Terpenoids and Quinones were commonly observed from both extracts. The better inhibitory activity was observed while using methanol extract and most of the isolates were suppressed with 7.5mg of concentration. This plant extracts which proved to be potentially effective can be used as antibacterial agents against MRSA.