Evaluation of In vitro Antifungal potential and Gc-Ms Analysis of Acalypha indica (L.)


Mahakavi, T & Bakiyaraj, R 
Department of Botany, Government Arts College (Autonomous), Karur, Tamil Nadu, India.

Baskaran, L
Department of Botany, Government Arts College, Salem, Tamil Nadu, India.

Santhoshkumar, M
Deparment of Botany, Joseph Arts and Science College, Thirunavalur, Tamilnadu, India.


In this study chloroform and ethanolic stem extracts of Acalypha indica were examined for phytochemical, GC-MS analysis and antifungal activities that use the disc diffusion method against two fungal species, including Aspergillus niger and Fusarium solani. A preliminary phytochemical screening was found in the both extracts using standard qualitative procedures that revealed the presence of the alkaloids, flavonoids, tannins, phenols, glycosides, saponins, catachols, coumarins, terpenoids and quinones present in the chloroform and ethanol. Antifungal activities of the ethanolic extracts was assessed by disc diffusion assay and exhibited strong inhibitory activity against the Aspergillus niger and Fusarium solani produced inhibition zone ranging from ethanolic extract 20.10±0.60 and 18.37±0.55mm. The minimum inhibition was recorded with the extract of chloroform 17.36±0.52 and 15.66±0.45 mm on tested fungi, whereas the ethanolic stem fraction was subjected to GC-MS analysis for the identification of various antifungal and antioxidant constituents. Twenty compounds were identified through GCMS analysis of this fraction. Among these, eight compounds possessed antifungal and antioxidant properties as reported in literature.